The main purpose of the Empowering Nonprofits Act is to provide financial relief to certain nonprofit organizations by reducing their cost-sharing requirements for federal grants. This aims to support these organizations in their efforts to serve communities, particularly in areas with high poverty levels. The key provision of this legislation mandates that, for a period of five years after the law is enacted, executive agencies must reduce the cost-sharing requirement by 25 percent for eligible nonprofit organizations that receive federal grants.