The purpose of this legislation is to change how the National Institutes of Health (NIH) funds research that involves live animals. Specifically, it aims to stop the NIH from providing financial support for any research activities that use live animals unless those activities take place within the United States. This is intended to ensure better oversight and animal welfare standards in research funded by American taxpayers. The key provisions of this legislation include a clear prohibition on NIH support for research involving live animals conducted outside the U.S.